A low or moderate expired tidal volume can be difficult to achieve during noninvasive ventilation for de novo acute hypoxemic respiratory failure. To see if this is a cause for concern, Carteaux et al set out to assess expired tidal volume and its association with noninvasive ventilation outcome.
They found that a low expired tidal volume is almost impossible to achieve in the majority of patients receiving noninvasive ventilation for de novo acute hypoxemic respiratory failure, and a high expired tidal volume is independently associated with noninvasive ventilation failure.
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