Tag Archives: Sodium Bicarbonate

Does Sodium Bicarbonate Prevent Kidney Injury After Cardiac Surgery?

Up to 50% of all patients requiring cardiopulmonary bypass during cardiac surgery develop acute renal failure, with less than 5% requiring renal replacement therapy. Consequently, post-cardiac surgery acute kidney injury (AKI) is associated with increased morbidity and mortality. In the July Critical Care Medicine, McGuinness and colleagues designed a multicenter Phase IIb trial to test the hypothesis that a perioperative infusion of sodium bicarbonate might attenuate AKI in cardiac surgery patients. Read more…