Tag Archives: appraisal

Targeted Temperature Management After Cardiac Arrest: How Low to Go?

Previous trials including Bernard SA, Gray TW, Buist MD, et al and a study by the Hypothermia after Cardiac Arrest Study Group have demonstrated a significant improvement in neurological function and survival when therapeutic hypothermia was employed following cardiac arrest. The optimal temperature remains unclear, and the mere avoidance of hyperthermia may explain the benefit of hypothermia when it is induced after arrest. In the November issue of the New England Journal of Medicine, the TTM (Target Temperature Management) Trial Investigators, led by Niklas Nielsen in Sweden, conducted a trial to investigate the benefits and harms of two temperature regimens for cardiac arrest patients.

Read more…