Surviving Sepsis Campaign Six-Hour Bundle Revised

The leadership of the Surviving Sepsis Campaign (SSC) has believed since its inception that both the SSC guidelines and the SSC performance improvement indicators will evolve as new evidence improves our understanding of how best to care for patients with severe sepsis and septic shock.

With publication of the results of the Protocolized Care for Early Septic Shock (ProCESS) trial, the Australasian Resuscitation in Sepsis Evaluation (ARISE) trial, and the Protocolised Management in Sepsis (ProMISe) trial, the SSC Executive Committee has revised elements of the six-hour bundle.

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