Passive leg raising creates a reversible increase in venous return, allowing for the prediction of fluid responsiveness. However, the amount of venous return may vary in various clinical settings, potentially affecting the diagnostic performance of passive leg raising. Therefore, Cherpanath et al performed a systematic meta-analysis determining the diagnostic performance of passive leg raising in different clinical settings with exploration of patient characteristics, measurement techniques and outcome variables.
They found that passive leg raising retains a high diagnostic performance in various clinical settings and patient groups. They also found that the predictive value of a change in pulse pressure on passive leg raising is inferior to a passive leg raising-induced change in a flow variable.
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