Impact of Initial CVP on Outcomes of Fluid Management Strategies in ARDS

In acute respiratory distress syndrome, conservative fluid management increases ventilator-free days without affecting mortality. Response to fluid management may differ based on patients’ initial central venous pressure. Semler et al hypothesized that initial central venous pressure would modify the effect of fluid management on outcomes.

They found that conservative fluid management decreases mortality for acute respiratory distress syndrome patients with a low initial central venous pressure.

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