Critical eConnections  |   My SCCM  |   Learn ICU  |   Patients & Families

January 19, 2017

Concise Critical Appraisal

Effects of Epinephrine on Cerebral Oxygenation during CPR


Check Out Congress with Critical Connections Live


Listen to the Latest iCritical Care Podcasts
Effects of Epinephrine on Cerebral Oxygenation during CPR

Epinephrine has been presumed to improve cerebral oxygen delivery during cardiopulmonary resuscitation (CPR), but animal and registry studies suggest that epinephrine-induced capillary vasoconstriction may decrease cerebral capillary blood flow and worsen neurological outcome. The effect of epinephrine on cerebral oxygenation during CPR has not been documented in the clinical setting. Therefore, Deakin et al examined the effect of epinephrine on cerebral brain oxygenation during in-hospital cardiac arrest.

They found that 1 mg intravenous epinephrine, administered during advanced life support resuscitation, was not associated with a clinically significant change in cerebral tissue oxygenation.

Read the full Concise Critical Appraisal by logging into the SCCM eCommunity. Concise Critical Appraisal is a regular feature aimed at highlighting the best and most relevant literature from a variety of academic journals and encouraging discussion around recent studies and research.

Tags: , , , ,
Back to Top
Check Out Congress with Critical Connections Live

Can’t join us in Hawaii? You can still be part of the late-breaking and most controversial sessions from the Society of Critical Care Medicine’s (SCCM) 46th Critical Care Congress. Tune in Monday, January 23, 2017, for Critical Connections Live.

Visit and follow hashtag #SCCMLive. Programming begins at 1:00 p.m. Eastern Standard Time (EST) (see more time zones).

To receive a reminder to tune in, please provide your contact information.

Critical Connections Live Program Schedule

1:00 p.m. – 1:30 p.m. EST
Congress highlights and interviews with key members of the critical care community, SCCM leaders and attendees.

1:30 p.m. – 2:45 p.m. EST
Hot Topics and Late-Breaking Science: Physician-Assisted Suicide and Euthanasia in the Intensive Care Unit: A Dialogue on Core Ethical Issues
Jan Bakker, MD, PhD, FCCP, and E. Wesley Ely, MD, MPH, FCCM

Live Post-Session Discussion Panelist #SCCMLive
Mitchell M. Levy, MD, MCCM

2:45 p.m. – 4:30 p.m. EST
Congress highlights and interviews featuring key sessions from Sunday’s opening session.

4:30 p.m. – 5:45 p.m. EST
International Guidelines for the Management of Sepsis and Septic Shock: 2016
Laura E. Evans, MD, FCCM, Andrew Rhodes, FRCP, FRCA, FFICM, and Mitchell M. Levy, MD, MCCM

Live Post-Session Discussion Panelists #SCCMLive
Lauren Epstein, MD, and R. Phillip Dellinger, MD, MCCM

Live from Congress Hosts
Richard H. Savel, MD, FCCM, and Christopher L. Carroll, MD, MS, FCCM

Tags: ,
Back to Top
Listen to the Latest iCritical Care Podcasts

If you haven’t checked out our iCritical Care podcasts, listen to the latest releases and subscribe! Loyal listeners and newcomers, be sure to rate us on iTunes. Learn more at

SCCM Pod-332 Dexmedetomidine Use in Critically-Ill Children with Acute Respiratory Failure

SCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches

SCCM Pod-330 Long-Term Mental Health Problems After Delirium in the ICU

SCCM Pod-329 A Bedside Model for Mortality Risk in Pediatric Patients with ARDS

SCCM Pod-328 Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials

Tags: ,
Back to Top

Register for an Industry Education Workshop