Delirium and the Efficacy of Dexmedetomidine

Some contend that effective therapy has not been established for patients with agitated delirium receiving mechanical ventilation. Therefore, Reade et al set out to determine the effectiveness of dexmedetomidine when added to standard care in patients with agitated delirium receiving mechanical ventilation.

They found that among patients with agitated delirium receiving mechanical ventilation in the intensive care unit, the addition of dexmedetomidine to standard care (compared with standard care alone [placebo]) resulted in more ventilator-free hours at seven days.

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