Assessing Tissue Oxygenation and Microvascular Reactivity in ICU Patients

Impaired microcirculatory perfusion and tissue oxygenation during critical illness are associated with adverse outcome. The aim of a study by Donati et al was to detect alterations in tissue oxygenation or microvascular reactivity and their ability to predict outcome in critically ill patients using thenar near-infrared spectroscopy (NIRS) with a vascular occlusion test (VOT).

They found that in critically ill patients, NIRS with a VOT enables identification of alterations in tissue oxygen extraction capacity and microvascular reactivity that can predict mortality.

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